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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82066bfbb28cc8c1fbb8ed7bb7cdb63e5c1492ebcbd6d7003af62e4bec055071' 
  AND token = '4AanfpE7TUEvaOoeiOCU4PwvY6pHwTZUJ240le+9zd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}