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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fd049b25ef840f74320780940c460b643cb816f2ff0e88d3e63005cc9840eda' 
  AND token = 'xoSY4+RxHfltcuklMJyAK5KJdxuHIQQO9G2qfXZTHE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}