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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f5a7662c2a7679efc2149e82bd455cfc9b61985f7e9fb54189eb3774cb7b59a' 
  AND token = 'pJ0DFy45akKvqq+iDgmgkEh16V7S3sLeTWeAtbIfBKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}