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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6490fb77f4f81ce16064a1ffad0e257726210009d34378c251141da91b4572e1' 
  AND token = '/Yp9fB3FxTZi6xPTtbDH+JpoCvEysiyGpD41kPr6BTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}