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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e4e8bdd8449d6fe7f36cc0b1d820681f5d438d9a19ceae2b8023c6c5619486' 
  AND token = '5Ihb1FkfB0eHsMc0rQ7wIZUusiOTjTgB6oojOlUNgos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}