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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0626fccdc801e0acbf52b82f2303ae39bd19da9dc489180e4c329873f3588995' 
  AND token = 'ABtEVab56vjH99osLTGvC5KAU250CF2us4LXe6IREWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}