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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdce03f059e2c862f512dee5c97f5d1d50263184007232697039460c779db745' 
  AND token = 'kb5rywcmcXT3JLMMkenwVWHu5aIE9J2shTAXlB7brj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}