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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395511c13f7cbe7c642dc2a722abdf5e3ee8f42bf4a08951eef9516a6e130a15' 
  AND token = 'ZtGNkyLsG/bAKzt2LkaPPrhHEo59t3cBmeuq+iF54wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}