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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7f5fc6abd035bad32a7aab2b6d6842075011be3e16983b0c577dea0a19748e' 
  AND token = '2TTnj5m/9ECRGurpiM99KLoMql/3DMKFkPvY73+xkng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}