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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '103c5216a0e4af33a1c2fb051bac1dc69568e5f18e1e4a7ee99b5226501431ad' 
  AND token = 'uK+0IFjEuegn0iO7o06fTdXEOKXBGJXUekWb5IehTaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}