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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661cacd7bfcad3f4c1c994c30dea9d200200c10fccbc8acf746e9216de41db63' 
  AND token = 'ecwFye3CknSzTmCd2wWkvtJsj07JI1IYeCEcaVOCQIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}