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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df7bc0dd83fe20f0e3c4fc9290a810c09e938510f62274d54abaf5770d32cb3' 
  AND token = 'CUWZPi4NXEDaooHvS0MQx+3z3P/wYLgh8NWQE6WNPq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}