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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1fedc961305a764cdf86b6a1ff2c6f3920d1e6872e1f86dd3d65991d0cfd535' 
  AND token = 'pGkHmoRBuRtw2mmHQpjOlMiagL0pTnamPuY9MxMFLuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}