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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e345f90526f98273fcb850cc8233d2318293511f6feed881d349bfa06d608d8d' 
  AND token = 'Hf4NUrYNjYEaePKCvURD9ECZLh8Zpx5Dghs2NWPJ7Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}