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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd2541260fb53ad6f017f4d02f4425861e0bbaf07f1d0964927b28e3e5dd3816' 
  AND token = 'xZ+Hi9+aw1ldSKdxmzawL8XhH6TsL9/TXKmI0wCeVWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}