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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c033681b11b84c0d02c0feba69687ff05ba3a0ef5b40b4898bfe095095ded97' 
  AND token = 'a/d4IfBJbSH2M0AT+VkOa6miKC6f2i5rAhoEW/iMgZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}