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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb809ba9ee66291c15d53e2200eb922d06e0cf9e351076c360161a8b19d9056b' 
  AND token = 'JWn4a7InwzSfrYzvJyT9CTc5byDHTYrmO0TPJWyy8IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}