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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99223cc29b7cd414a9fb25b001a8ffe824aa838c85a130546080c4d3d1bcfff' 
  AND token = 'Uf+gYFZKR8c8zNTzu/WW3zukzd5bb9dkE4Sy7QVrMUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}