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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a7a887829bc6171aa366c54db8659000d186b74736d145cbe213929bdc38de' 
  AND token = 'gIg+iWXsqMZ0cO0l2gzqVBlidV5KbqoSMg0fQdF2N8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}