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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35a2b5199548d8097940e599433e09c8ecc217078c43672a8e6d01e2eeea8d86' 
  AND token = 'dn03aKDh/mo1Oq7jIq6lkTXwzf0joGgaiI9ZVOPotL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}