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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49f9978c7c5fbc74705786fdbe28c35c70b0a9bf6c60edb1b5bcf7afe9c2e21' 
  AND token = 'stRgHFySHeMERXN8Pcmt1zYbdLWTOJHd5TGO/iouCvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}