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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38e1562699b4fdaa2b69d836c012e8e84666f0cda3db739287e748b606c4d880' 
  AND token = 'cjUTKBiGjC+iHsTRUij5tJ0rbShhS6L3omJnKPFXiPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}