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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d02a6d664a78c49edaf52f4e66346afbe98f42170ca0e73a7116903b2e7f98' 
  AND token = 'oHROK+tZX7AyFQSZ8iUGeO0ZmWonAqEPB4ksJ7bTTy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}