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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd59c366a06d6f92277ee1d3ffee6e6f531918c81fcc7004232e06c0b2b10620' 
  AND token = 'jEN2iOmxEg73j0EbZwwO+gk0Ah2qSUwZw6f/68lWIkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}