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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2fc386fd42a7f4c71625ae679ca8addaeb7e03dad8c2ceaf5449f81345fe7e' 
  AND token = 'MFsjuvK/pK8OBrcp4sA9w9FXKLymyS9V4FXWxqD715I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}