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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f2f4ba8ffab256eed3ab55021838e4dcfac36eb168d9709496db8e8deb7914' 
  AND token = 'YyILwePzZ+VrJYg33lHxzvTZ7RaX97kmNIf12oyra14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}