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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8656f26b67a7ef03b098746cdd6e3f8cf6d9e0dd312c5e87d319b249abc6f3e1' 
  AND token = 'Stp/TCIMC9QxfaflwUl9YM8su3d7AdG6cBWCDuWt/PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}