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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '281ad42c6e79f538c222ed466e221889b7bd77de070eb56cc96de681e7e7e069' 
  AND token = 'D7oGV27oXpJqdBiIAdbxu4YAQBB/FACH269WdxMBlq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}