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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8676d1e9dee53dbfc1d71d00029559673282ee501a34db4727ac01770b5be22c' 
  AND token = 'gWi64/Y9meUpLpkI6rCgT9DdhmnRtMh1izQapHu59e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}