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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac9ed7d516d54687c38746465d1716c8324852a48e0b93f570e72868e28bb1d' 
  AND token = 'CLJo+VO0Vp+K9GA0WB6PNUkVIidWfws9+qy5r4CVJLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}