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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f912f6dc1d50c1fde68442c919432b4ab94b7b0f65a31de0a5bab9d359371a8a' 
  AND token = 'yleKH7cwv7twIZItLJnBLCn2kUlFLk6yUUEcAJqw0P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}