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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea92d246d60d6cf6577278a6ca90bf7618769554c525263d179da9165f228cd7' 
  AND token = 'bIoTPS1w9VHlB8DdvAuYfPlUdwE0vDkeZJot8+KS0Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}