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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defc4225488961ef5c0f7c5bf53e2f145636f9fcc610bfa2230ede2e44c1fef9' 
  AND token = '+Yr4RmMwpufBwf68c5ugzn4eIegqzRdztft4nDD6BO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}