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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e42c36a3120ff3b886a0f8eb49ca283c4756677732e8334312da1500d29a488' 
  AND token = 'scghWf5ssz4hZtoWtbq8Wz0Q6RDh3/T+vbSL89mQzog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}