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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac41826ae0739ea081af440143ab21e5dd95cc700279cdb07d60f37298cc7cd7' 
  AND token = 'rOEZoXMR+oQgrcXIwy7cxlEQLL5RqlOSi9OxUGMCtqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}