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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6530fedf4976d2807927390f7859ecc793e6ba2bc224c58a4966f7688d6a08c9' 
  AND token = 'V05yrjKqTc2G7IlYxI2hgWIwnhMnVSUEXxmG5TL2yz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}