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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fb3c5b86fba16c8dc63ed195f29611e8cd58ca0ce535e9cc916f58757d2b379' 
  AND token = 'mk8/w0vHsM5pLdu369G1RlX0DmDZV35PqXwzgoPHfiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}