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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d48cee05b26cdac7cfe6a621890b9340ed9576ddb78790e72c55e2c4c6c415d' 
  AND token = 'hE7U1yx2OJZBC9DyBB2iPjIhMfB7LKsm6y+T7dNY8T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}