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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1fc46e6ba8fda33825167909238f1abcf8eddc428fdb587801b1bcf5bf4861' 
  AND token = '7W8MkefNdmA0c+i2Y7mHM9rRChkPdQ0lQEb8t3phLRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}