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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d823c5cbc2234a089cae6f10b722bfd1609eb8d9000945e250fdb5b52700a9c' 
  AND token = 'OIG8napatVak3LsVWx+zv1XPFrU8LP/r9On6iWVogrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}