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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016363bcf9db86f9dd056631ebc599068d0d0ffa6bd07095466cbf1be6359363' 
  AND token = '1CWDdNjpHTXu0Vlw0y+sk9ij0UICYHUIZ/sS8aCiJLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}