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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da8f144cd4f1fb313c203fee87308c22dbc267b42d4e71d813e3014e8194699' 
  AND token = 'tnF/bbPgdMJxx5DRIuTSOFWEx9lOaXuASNEeaYxckTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}