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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b3d80848d3a8c11722687285c19f99792f5404fec99bd3ae1587c40a547de1b' 
  AND token = 'xYF7FKqDy9qzpnyGkFeWaIx+uFSaNjWcBcGpm9Bamrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}