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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641e1a3c0c76b14631b8cfe2430d1e767b1747f7ebe949758e5a3ee0119d6945' 
  AND token = '/TlZ/wI67K14IMCIk44XVP99rABwHl4ebWYPmLhcEOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}