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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53581c7995f808b78741b82b259b6d1e765b250857ee3496ac742c6b1d434cb' 
  AND token = 'JZCWKl03kh72JuR2HUC8O0QoE5Qgt5Fzw+akT5s8ruw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}