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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8112d96a1f07bc095a24293f18f99f02f7bd41bc48e8e807a62edbaeca9eb1' 
  AND token = 'O2x6eoXKkjqQjiWNUmylFqhos+0b/eyuzap+modyD+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}