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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b61aa8b79ebefdf256fa31a9b1cdb1c85cb4a9bd2412feb13d81b0622350599e' 
  AND token = 'EBvClc8Rarf+zolLJkn0XlHu5Mn/iQVVhdtKa/8YP0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}