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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45fb362caa96a1192113d465692c281ff42e38391f479a106664e1dd288668d' 
  AND token = '71AUwPk4i54+pWneewEazo2FIJGlXm+4jSNXz1hEcpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}