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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3900e3139c5337db13a0ac73b69721a785a42b0c22f0c118fed8d3ff10f1ff' 
  AND token = '7m45vkuLYHrVtWgr/5MAnAZPIRsCuHz/RTW8f/4wivg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}