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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79d4941ebe6e035955e0b65b8a1c9b5cdb5c0c52eb1bfc75223b6a2c35b2465c' 
  AND token = 'D4L88ehy/uDixUQ3F66WTW6q7JtfEfn2CZKcnV5Y0R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}